This guide is a compiled list of the top-performing 2008-model year midsize cars in J.D. Power and Associates' key automotive research studies. The studies include the 2007 Vehicle Dependability Study (VDS), the 2007 Automotive Performance, Execution and Layout (APEAL) Study, and the 2007 Initial Quality Study (IQS). All models are listed alphabetically by manufacturer.

Ford Fusion: A brand-new model in 2006, the 5-passenger midsize Fusion sedan offers consumers the choice between front- and all-wheel drive (FWD and AWD), and 4- or 6-cylinder power. Replacing the previous-generation Taurus in the Ford lineup, the Fusion offers a more youthful and sportier alternative to the competition. New for 2008 is the Sport Appearance package, which adds upgraded suspension, 18-inch wheels, and minor cosmetic changes. In the 2007 IQS, the Ford Fusion ranked among the top three models in its segment, boasting a low number of manufacturing and design defects during the first 90 days of ownership. In standard trim (front-wheel drive, 4-cylinder engine), the EPA fuel-economy estimates for the Fusion are 20 mpg city/28 mpg highway. After the Fusion was updated with standard side and side curtain air bags for 2007, Ford added standard tire-pressure monitoring, standard anti-lock brakes (ABS), and voice activation to the optional navigation system for the 2008 model year.
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