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Pachman is an anticarcinogen. Administering pachman to mice (5mg/kg) by abdominal injection daily for ten consecutive days inhibits S180 with a 95% inhibit ...

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Fu Ling
Poria, Hoelen

Dosage
9-15g.

Toxicity
One known potential adverse effect of poria is epispasis, a kind of allergic reaction.(1)

Chemical Composition

Pachymic acid; Tumulosic acid; Trametenolic acid; Eburicoic acid; Dehydroeburicoic acid; Poricoic acid; b-amyrin acetate; Pachyman; Pachymaran; Glucan H11; Ergosterol; Caprylic acid; Undecanoic acid; Lauroic acid; Dodecenoic acid; Palmitic acid; Dodecenoate; Caprylate; Fumulosic acid methylester; Polyporenic acid C methylester; Pachymic acid methylester; 7, 9 (11)-dehydropachymic acid; 7, 9 (11)-dehydropachymic acid methylester; 3b-hydroxy-lanosta-7, 9 (11), 24-trein-21-oic acid; 3b-hydroxy-16a-acetyloxylanosta-7, 9 (11), 24-trien-21-oic acid; 3b-,16a-dihydroxylanosta-7, 9 (11), 24 (31)-trien-21-oic acid methylester.(2),(3),(4),(5),(6),(7),(8),(9)

Pharmacology

Anti-neoplastic effect

Pachman is an anticarcinogen.(10) Administering pachman to mice (5mg/kg) by abdominal injection daily for ten consecutive days inhibits S180 with a 95% inhibition rate.(11)

Enhancing immunity

Oral-feeding pachman to mice (250, 500, 1000mg/kg) daily for seven consecutive days enhances the phagocytic function of macrophage of both healthy and cancerous mice.(12)

Diuretic effect

Administering alcohol-based extract of this herb to rabbits at 0.5g/kg daily for five consecutive days shows a diuretic effect.(13),(14)

Calming effect

Administered at the dosages of 5, 10, 20g/kg, the water decoction of fushen, a variation of this herb (with pine roots growing into it), counteracts the caffeine-induced excitation in mice.(15)

Protecting the liver

Injecting poria injection into hamsters at 1.4g/kg daily for eight consecutive days can counteract carbon tetrachloride-induced liver damage.(16)

Antibacterial

Experiments show that the 100% water decoction of this herb inhibits Staphylococcus aureus, Bacillus coli, and Bacillus proteus.(17)

References

Liu Xue Ru, et al. China Journal of Hospital Pharmacy. 1992;12(8):379.
Wang Li Wa, et al. Journal of Chinese Materia Medica. 1998;29(3):145-148.
Li Yu Qi. Practical Journal of Combining TCM & Western Medicine. 1998;11(7):643.
Pan Qi, et al. Journal of Yunnan College of TCM. 1998;21(4):20-21.
Pan Qi, et al. Journal of Yunnan College of TCM. 1999;20(1):33-34.
Wang Li Ya, et al. China Journal of Chinese Medicine. 1993;18(10):613.
Guo Xin Fang, et al. Journal of Contemporary Chinese Medicine. 1993;4(1):15.
Cai Chuan Ying, et al. Journal of Chinese Materia Medica. 1984;15(2):61.
Lin Si Lan, et al. China Journal of Chinese Medicine. 1991;16(4):222.
Zhou Mei Xiu. Fujian Journal of Medicine. 1982;4(4):back cover.
Chen Chun Xia. Journal of Chinese Materia Medica. 1986;16(4):40.
Lu Su Cheng, et al. Journal of No. 1 Military Academy. 1990;10(3):267.
Lu Ding, et al. Journal of China Medical Academy. 1987;9(6):433.
Lu Ding, et al. Journal of China Medical Academy. 1988;10(4):294.
Hu Chong Jia. Journal of Wuhan Medical College. 1957;(1):125.
Han De Wu, et al. China Journal of Internal Medicine. 1977;2(1):13.
Nanjing College of Pharmacy. Materia Medica, vol. 2. Jiangsu: People's Press; 1976.

This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.

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