The formula is mainly used to treat hyperthyroidism with hyperactivity of the liver-yang. Its indications are vexation, hyperhidrosis, restlessness, tendency towards anger, dysphoria with feverish sensation in the chest, palms and soles, dry throat and mouth, exophthalmus, weight loss, and a rapid and taut pulse.
Yang, et al. used Jia Kang Ling Pian to treat 150 cases of hyperthyroidism with yin deficiency-induced yang hyperactivity. They achieved relatively good clinical and therapeutic results. The occurrence rate of side-effects is significantly lower than that of tapazole.(2)
Liao, et al. used Jia Kang Ling to treat 60 cases of hyperthyroidism, achieving a total effective rate of 96.7%.(3) Liu, et al. used slightly-modified Jia Kang Ling formula to treat 41 cases of hyperthyroidism and reported a total effective rate of 85.4%. Their formula consisted of Duan Long Gu, Duan Mu Li, Huai Shan Yao, Han Lian Cao, Xia Ku Cao, and Zi Dan Shen.(4)