All Topics > Health > Traditional Chinese Medicine Herb > Mu Dan Pi >

Mu Dan Pi Georgia

Local Companies

Katy Gillis Personal Trainer
678-255-5748
2005 T Lake Park Dr SE
Smyrna, GA

Gold's Gym
770-382-4653
650 Henderson Drive
Cartersville, GA

Yoga for Exercise
678-230-7099
210 Dahlonega St. Suite 205
Cumming, GA

About Movement Pilates Studio
404-373-9672
431 W Ponce de Leon Ave
Decatur, GA

Cor Pilates
478-477-2678
4725 A Northside Dr.
Macon, GA

Karen's Pilates & Yoga
478-731-8879
15 Camilla Ct.
Macon, GA

SportsTowne
478-314-3000
170 Starcadia Circle
Macon, GA

yoga for exercise
678-230-7099
101 meadow dr., suite b
cumming, GA

Yoga for Exercise
678-230-7099
101 Meadow Drive
Cumming, GA

CrossFit Decatur
404.370.1763
701 Church St
Decatur, GA

Mu Dan Pi
Moutan Radicis Cortex, Moutan

Dosage
6~9g for oral decoction, or for pill and powder.

Toxicity
LD50 (mice/peritoneal injection): 735mg/kg (paeonol oil); 6.9mg/kg (paeonol sodium sulfonate).(1)

Chemical Composition
Paeoniflorin; Oxypaeoniflorin; Benzoylpaeoniflorin; Benzoyloxy-paeoniflorin; Paeonol; Paeonoside; Paeonolide; Aplopaeonoside; 2Â£-3-di-hydroxy-4-methoxyacetophenone; 3-hydroxy-4-methoxyacetophenone; 1Â£-2Â£-3Â£-4Â£-6-pentagalloylglucose.(2)

Precautions
Patients with the following conditions should avoid using this herb: blood deficiency syndromes, cold of the deficiency type, hypermenorrhea, or pregnancy. There has been one report of side-effects: when 5% Mu Dan Pi cream was used to treat acute localized eczema, local red spots, itch, and burning sensation were experienced by some patients.(3)

Pharmacology

Analgesic effect

Experiments show that paeonol has a significant analgesic effect on mice. Paeonol was administered to mice via subcutaneous injection for 7 days. Hot plate test was used to measure the pain threshold. The results suggested that paeonol induced analgesia causes no drug resistance. Both tail-erection reaction test and jumping reaction test showed negative results, when mice were given paeonol via subcutaneous injection. Hot plate test showed that the analgesic effect of paeonol can not be reversed by naloxone.(4)

Anti-inflammatory effects

In mice, dimethylbenzene-induced auricle inflammation can be inhibited effectively by gastrolavaging Mu Dan Pi decoction at dosages 10g/kg, 20g/kg, or 40g/kg. Also, feet swelling that is caused by carrageenin, formaldehyde, or egg white can be significantly inhibited by intraperitoneal injection of Mu Dan Pi at 15g/kg or 30g/kg. The effects are dosage-dependent.(5)

Effects on the blood system

Total glycoside of Mudanpi (TGM) can protect RBC, inhibit platelet aggregation, increase the cAMP level in blood platelets, counteract atheroscleorsis, and promote local microcirculation.(6),(7),(8),(9) It can inhibit H202-induced hemolysis. Low concentrations of TGM inhibits osmotic hemolysis, while in higher concentration (100mg.L-1), it promotes osmotic hemolysis. TGM inhibits H202-induced consumption of reduced glutathione in RBC and the production of lipide peroxide. Experiments show that paeonol can inhibit platelet aggregation both in vivo and in vitro.

Liver-protective effect

Experiments show that in mice with carbon tetrachloride or ethanol-induced liver damages, TGM (20mg/kg-1) can significantly inhibit the increase in serum SGPT and the generation of lipide peroxid.(10)

Effect on immunological functions

Paeonol, given by i.g. 200mg/kg for 5 consecutive days, can reduce the weight of immune organs in mice, increase carbon clearance, relieve delayed hypersensitivity, and decrease the hemolysin antibody level in the spleen. In mice, it can significantly inhibit lymphocyte proliferation in the spleen that is induced by LPS and by Con A in sub-suitable concentrations. Paeonol (50Â¦Ìg/ml) can also, in vitro, significantly inhibit the proliferation of mice's experimental spleen lymphocytes.(11) In low concentrations (10-15mg/kg), paeonol functions to increase the percentage of lymphocyte with positive (-ANAE and promotes the release of leukocyte migration inhibitory factor in peripheral circulation, thereby improving the cellular immunity. Furthermore, it could promote the phagocytosis of peripheral neutrophil on Staphylococcus aureus, thereby enhancing nonspecific immunity.(12)

Effects on the cardiovascular system

Paeonol has a significant and immediate inhibitory effect on delayed I K, I Na, I Ca T, and I Ca L. The effect can be observed within 1 minute of administration, and it shows a dose-effect correlation and a good reversibility.(13) When paeonol was given by intraperitoneal in a dose of 160.80mg/kg for 7 days to rats with myocardial reperfusion injury, it showed significant anti-arrhythmic effect on the animals. Its mechanism is probably related to anti-oxidation free radicals.(14)

Other actions

Experiments show that paeonol can slow down the gaining of body weight in animals. The body temperature of normal mice was decreased by 2.9Â¡æ within 30 minutes after the peritoneal injection of paeonol (200mg/kg). It has an antipyretic effect on the fever induced by choler-typhoid-paratyphoid vaccine.(15)

References

Wang Qi Bao, et al. Journal of Chinese Materia Medica. 1983;(10):26.
Editorial Committee of Chinese Materia Medica. State Drug Administration of China. Chinese Materia Medica. Shanghai: Science and Techonology Press; 1998.
Tang Hong Shan. Journal of Chinese Materia Medica. 1983;24(10):19.
Liu Xue Jun, et al. Chinese Pharmacology Bulletin. 1993;9(6):464-467.
Wu Guan Zhong,et al. Journal of University of Pharmacology of China. 1990;21(4).
Gao Ben Po, et al. China Journal of Pharmacology. 1992;8(3):202-205.
Dai Ming, et al. China Journal of Chinese Medicine, 1999;24(8):488-490.
Shi Ling, et al. China Journal of Pharmacology. 1988;9(6):555.
Ye Zhi Yi, et al. China Journal of Blood Rheology. 1999;9(3):137-138.
Dai Li Ming, et al. China Journal of Pharmacology. 1994;10(1):58-59.
Wang Xing Wang, et al. Journal of Pharmacology and Clinical Application of TCM. 1992;8(2):29-30.
Li Feng Chun, et al. China Journal of Integrated Medicine. 1994;14(1):37-38.
Hu Qian, et al. Journal of Physiology. 1994;46(6):575-580.
Zhang Guang Qin, et al. Journal of University of Pharmacology of China. 1997;28(4):225-227.
Wang Qi Bao, et al. Journal of Chinese Materia Medica. 1983;(10):26.

This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.

Featured Local Company

Katy Gillis Personal Trainer

Personal Trainer in Atlanta just for Women!

678-255-5748
2005 T Lake Park Dr SE
Smyrna, GA
http://www.katygillis.com

Hi! My name is Katy Gillis I am a Certified Personal Trainer just for women who are serious about living a healthy lifestyle and attaining their fitness goals through weight-training and cardio, nutrition, and overall health wellness coaching.

My Career:
I have dedicated my career to this wonderful lifestyle we call fitness and am ready to train you in all the areas you need.
I am an in-home CPT and have done workouts in the park, up the mountain, in the front yard, or in the small area cleaned out in the man-pit…wherever we have room to stand is room enough..
I bring all the equipment, you have nothing to bring except your body and a positive attitude. If you follow everything I teach you, the excess weight will come off and you will feel like a new women.
I have trained business women, stay-at-home moms and mom-to-be’s, models, and bride-to-be’s. Anywhere a woman is in her life is the perfect time to start.

Now It’s Your Turn!
I am excited to meet you but more so about watching you achieve the body you want.
Let’s start today, contact me to schedule your complementary in-home consultation*
Remember: This body is the only one you’ll ever have.
Make the most of your life now!

Sincerely,

Katy Gillis
CPT, Fitness Coach
katygillis@gmail.com
678-255-5748
www.katygillis.com

*Serious prospects only need apply.
Check out my website for news and tips as well as my calendar of events in the Atlanta area.

– Katy Gillis Personal Trainer

Read more about Mu Dan Pi

- A Brain In Belly Georgia

It turns out that these slang phrases actually have a solid, scientific basis. Medical research has proven that there is a second brain in the body and it's located in the belly.

- How to stay healthy during flu season Georgia
- "B" Vitamins Georgia
- 10 Tips for Healthy Living Georgia
- 4 Tips For Anchoring Georgia
- 7-Keto Dehydroepiandrosterone (DHEA) Georgia
- 5-Hydroxytryptophan (5-HTP) Georgia
- 3 Steps To Great Abdominal Strength Georgia
- 10 warning signs every parent must know Georgia
- Common Cold: Fact or Myth Georgia

Regional Articles

- Mu Dan Pi Acworth GA
- Mu Dan Pi Albany GA
- Mu Dan Pi Alpharetta GA
- Mu Dan Pi Americus GA
- Mu Dan Pi Athens GA
- Mu Dan Pi Atlanta GA
- Mu Dan Pi Augusta GA
- Mu Dan Pi Austell GA
- Mu Dan Pi Baxley GA
- Mu Dan Pi Blairsville GA
- Mu Dan Pi Brunswick GA
- Mu Dan Pi Buford GA
- Mu Dan Pi Calhoun GA
- Mu Dan Pi Canton GA
- Mu Dan Pi Carrollton GA
- Mu Dan Pi Cartersville GA
- Mu Dan Pi Cedartown GA
- Mu Dan Pi Chatsworth GA
- Mu Dan Pi Columbus GA
- Mu Dan Pi Conyers GA
- Mu Dan Pi Cordele GA
- Mu Dan Pi Covington GA
- Mu Dan Pi Cumming GA
- Mu Dan Pi Dacula GA
- Mu Dan Pi Dahlonega GA
- Mu Dan Pi Dallas GA
- Mu Dan Pi Dalton GA
- Mu Dan Pi Dawsonville GA
- Mu Dan Pi Decatur GA
- Mu Dan Pi Douglas GA
- Mu Dan Pi Douglasville GA
- Mu Dan Pi Dublin GA
- Mu Dan Pi Duluth GA
- Mu Dan Pi Eatonton GA
- Mu Dan Pi Elberton GA
- Mu Dan Pi Ellenwood GA
- Mu Dan Pi Ellijay GA
- Mu Dan Pi Evans GA
- Mu Dan Pi Fairburn GA
- Mu Dan Pi Fayetteville GA
- Mu Dan Pi Fitzgerald GA
- Mu Dan Pi Flowery Branch GA
- Mu Dan Pi Forest Park GA
- Mu Dan Pi Fort Benning GA
- Mu Dan Pi Fort Valley GA
- Mu Dan Pi Gainesville GA
- Mu Dan Pi Griffin GA
- Mu Dan Pi Grovetown GA
- Mu Dan Pi Hartwell GA
- Mu Dan Pi Hephzibah GA
- Mu Dan Pi Hinesville GA
- Mu Dan Pi Jesup GA
- Mu Dan Pi Jonesboro GA
- Mu Dan Pi Kennesaw GA
- Mu Dan Pi Kingsland GA
- Mu Dan Pi La Fayette GA
- Mu Dan Pi Lagrange GA
- Mu Dan Pi Lawrenceville GA
- Mu Dan Pi Lilburn GA
- Mu Dan Pi Lithia Springs GA
- Mu Dan Pi Lithonia GA
- Mu Dan Pi Loganville GA
- Mu Dan Pi Mableton GA
- Mu Dan Pi Macon GA
- Mu Dan Pi Marietta GA
- Mu Dan Pi Mcdonough GA
- Mu Dan Pi Milledgeville GA
- Mu Dan Pi Monroe GA
- Mu Dan Pi Morrow GA
- Mu Dan Pi Moultrie GA
- Mu Dan Pi Newnan GA
- Mu Dan Pi Norcross GA
- Mu Dan Pi Peachtree City GA
- Mu Dan Pi Powder Springs GA
- Mu Dan Pi Ringgold GA
- Mu Dan Pi Riverdale GA
- Mu Dan Pi Rockmart GA
- Mu Dan Pi Rome GA
- Mu Dan Pi Rossville GA
- Mu Dan Pi Roswell GA
- Mu Dan Pi Saint Simons Island GA
- Mu Dan Pi Savannah GA
- Mu Dan Pi Sharpsburg GA
- Mu Dan Pi Smyrna GA
- Mu Dan Pi Snellville GA
- Mu Dan Pi Statesboro GA
- Mu Dan Pi Stockbridge GA
- Mu Dan Pi Stone Mountain GA
- Mu Dan Pi Suwanee GA
- Mu Dan Pi Thomaston GA
- Mu Dan Pi Thomasville GA
- Mu Dan Pi Thomson GA
- Mu Dan Pi Tifton GA
- Mu Dan Pi Toccoa GA
- Mu Dan Pi Tucker GA
- Mu Dan Pi Valdosta GA
- Mu Dan Pi Vidalia GA
- Mu Dan Pi Villa Rica GA
- Mu Dan Pi Warner Robins GA
- Mu Dan Pi Waycross GA
- Mu Dan Pi Winder GA
- Mu Dan Pi Woodstock GA

- 7-Keto Dehydroepiandrosterone (DHEA) Georgia

Not to be confused with DHEA, 7-keto DHEA is a slightly different form of the DHEA molecule.

- 3 Steps To Great Abdominal Strength Georgia
- 4 Tips For Anchoring Georgia
- 10 Tips for Healthy Living Georgia
- "B" Vitamins Georgia
- Common Cold: Fact or Myth Georgia
- 5-Hydroxytryptophan (5-HTP) Georgia
- How to stay healthy during flu season Georgia
- A Brain In Belly Georgia
- 10 warning signs every parent must know Georgia

Related Local Events

Advisory Committee on Immunization Practices (ACIP)
Dates: 2/24/2010 - 2/25/2010
Location: Centers for Disease Control and Prevention, Tom Harkin Global Communications Center
Atlanta, GA
View Details

Advisory Committee on Immunization Practices (ACIP)
Dates: 6/23/2010 - 6/24/2010
Location: Centers for Disease Control and Prevention, Tom Harkin Global Communications Center
Atlanta, GA
View Details

Advisory Committee on Immunization Practices (ACIP)
Dates: 10/27/2010 - 10/28/2010
Location: Centers for Disease Control and Prevention, Tom Harkin Global Communications Center
Atlanta, GA
View Details

Advisory Committee on Immunization Practices (ACIP)
Dates: 2/23/2011 - 2/24/2011
Location: Centers for Disease Control and Prevention, Tom Harkin Global Communications Center
Atlanta, GA
View Details

Advisory Committee on Immunization Practices (ACIP)
Dates: 6/22/2011 - 6/23/2011
Location: Centers for Disease Control and Prevention, Tom Harkin Global Communications Center
Atlanta, GA
View Details

Advertising	Food & Beverage	Nightlife
Business Services	Franchise	Online Database
Career	Health	Pets
Cars	Holidays	Real Estate Resources
Computer Hardware	Home Appliances	Retail & Consumer Services
Construction	Home Electronics	Software
Education	Home Services	Technology
Entertainment	Industrial Goods & Services	Telecommunications
Environmental	Insurance	Trade Shows
Family	Internet	Travel
Fashion	Legal	Weddings
Financial Services	Miscellaneous	World History

Advertising	Family	Home Services	Real Estate Resources
Business Services	Fashion	Industrial Goods & Services	Retail & Consumer Services
Career	Financial Services	Insurance	Software
Cars	Food & Beverage	Internet	Technology
Computer Hardware	Franchise	Legal	Telecommunications
Construction	Health	Miscellaneous	Trade Shows
Education	Holidays	Nightlife	Travel
Entertainment	Home Appliances	Online Database	Weddings
Environmental	Home Electronics	Pets	World History