Tao RenSemen Persicae, Peach Kernel
| Dosage |
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To decoct, use 6-10g and grounded to powder.
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| Toxicity |
1. Depending on the mode of administration, amygdalin can be either harmless or poisonous - its toxicity level is at the highest when taken orally.( 1) 2. LD 50 (mice/abdominal injection/herb decoction): 222.5 ± 7.5g/kg.( 2) |
| Chemical Composition |
Triolein;
Triglyceride;
Glyceride;
1, 2-diacylglyceride;
Steroid Esters;
1, 3---diacylglyceride;
Monoacylglyceride;
Alkane;
Phosphorylcholine;
Phosphorylthanomin;
Linoeic acid;
Palmitic acide;
Oleic acid;
Amygdaloside;
Prunasine;
Saccharu;
Dextrose;
Steroid glycoside;
Acylate glycoside;
Asparagic acid;
Threonine;
Serine;
Glutamict acid;
r-propalanine;
Proline;
Aminoacetic acid;
Alanine;
Valine;
Methionine;
Isoleucine;
Tyrosine;
Phenylalanine;
Lysine;
Histidine;
Arginine;
Emusin;
Allantoinase;
Lactase;
Vitamin-B1;
Vitamin-K;
Nicotinic acid;
Camp;
Persicoside;
Naringenin;
3, 4-caffeic acid;
P-hydroxylauric acid;
Lactosdiglycerolglycocide;
Protein F, G, PR-A, PR-B;
Phospholipid Gp-1, Gp-2, Gp-3.( 3),( 4),( 5),( 6),( 7),( 8),( 9)
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| Precautions |
Contraindications: Pregnancy and patients without stasis.
Overdose can cause herb poisoning. In minor cases, poisoning symptoms include dizziness, nausea, lethargy, etc. In severe cases, respiratory paralysis can occur. There has been one reported incident of death by overdose.(10) |
| Pharmacology |
Administered to mice, water-based extract of Tao Ren can significantly inhibit alcohol-induced hepatico-glutathion depletion and lipid peroxidation, and protect the subjects against damages caused by peroxidation.( 11) Tao Ren can also reduce the level of lipid peroxide in the serum as well as in liver and brain tissues, and increase the activity of SOD.( 12) Tao Ren extract can significantly counteract hepatic fibrosis caused by CCl 4. By promoting the dissolution of collagen (types‡T, ‡V, ‡W and ‡X) as well as of fibronectin, Tao Ren can significantly reduce the formation of fibrous septa composed of collagenous fibers and reticular fibers, thus stimulating the recovery of hepatic tissues.( 13) Administered to mice (i.g. administration at 5.084g/kg for 4 days), Tao Ren can significantly counteract egg white-induced arthritis.( 14) Tao Ren has suppressive effects on fibroblast growth in in-vitro cell cultivation. Furthermore, it can suppress the proliferation of inflammatory cells and fibroblast hyperplasia in subjects of experimental trabeculae dissection .( 15) Tao Ren injection (HHI-I) can increase the partial pressure of oxygen in the subcutaneous tissue of the ischemic rabbit ear that is caused by direct skin incision. This promotes blood flow in the microcirculation of ischemic skin, thus aiding the recovery from the incision.( 16) Both in in vivo and in vitro models, Tao Ren can suppress the aggregation of platelets induced by the thrombin and diphosphric acid (ADP). This effect intensifies as the dose increases. In people with normal or high incidence of platelet aggregation, Tao Ren can significantly suppress the aggregation of platelets.( 17) Tao Ren can significantly promote the blood flow in dogs' femoral artery, reducing vascular resistance. Also it can significantly increase the flow of perfusate in exsomatized rabbit ear vessels, and counteract the contractile effect of levarterenol on the vessel.( 18) Tao Ren also has anti-allergic,( 19) liver-protecting,( 20) and intestine-lubricating effects.( 21) |
References
This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.
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