Treating simple edema in the lower limbs
Chen treated 27 cases of simple edema in the lower limbs with a modification of Wu Ling San. The modified formula consisted of Gui Zhi (Cinnamon Twigs), Fu Ling (Poria), Ze Xie (Alisma), Zhu Ling (Polyporus), Che Qian Zi (Plantain Seed), Bai Zhu (white Atractylodes), Fu Zi (processed Aconite), Niu Xi (Achyranthes), and Huang Qi (Astragalus). For those who had yellowish greasy tongue fur, Fu Zi was removed, and Fang Ji (Stephania) and Yi Yi Ren (Coix) were added. For patients with sublingual varices, Dan Shen (Salvia) and Chi Shao (Peony Red) were added. After treatment, in all 27 cases, swelling had subsided completely in 14 days (19 cases did so in 7 days).(
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Treating Meniere's syndrome
Ye treated 86 cases of Meniere's syndrome with a modification of Wu Ling San. The modified formula consisted of Gui Zhi (Cinnamon Twigs), Bai Zhu (Atractylodes), Ban Xia (Pinellia), Shi Chang Pu (Grassleaved Sweetflag Rhizome), Zhu Ling (Polyporus), Fu Ling (Poria), Ze Xie (Alisma), and Xian He Cao (Agrimony). The formula was further modified to suit individual patients' symptoms. The patients were administered one to two doses of the formula in a decoction daily and one course of treatment last a week. While under treatment, the patients were advised to avoid hot, cold, raw, and greasy foods. The results showed that 54 cases were resolved, 27 improved, and the remaining 5 did not respond to the treatment, with a total effectiveness rate of 94.2%.(8)
Treating infantile nervous micturition
Shi et al. treated 56 cases of infantile nervous frequency of micturition with modified Wu Ling San. The formula consisted of Fu Ling (Poria), Zhu Ling (Polyporus), Ze Xie (Alisma), Chai Hu (Bupleurum), Bai Zhu (Atractylodes), Sheng Ma (Cimicifuga), and Gui Zhi (Cinnamon Twigs). One dose of the formula in a decoction was administered daily. The results were, 55 cases were resolved and the remaining case did not respond to the treatment.(9)
Treating auditory vertigo
Tao treated 34 cases of auditory vertigo with Wu Ling San. For patients who were experiencing nausea and vomiting, Ban Xia (Pinellia) and Zhu Ru (Bamboo shavings) were added. For those suffering from dysphoria and severe palpitations, Gou Teng (Uncaria) was added. For patients who had a bitter taste in the mouth and a wiry pulse, Long Dan Cao (Gentiana Root) and Chai Hu (Bupleurum) were added. And for the patients with red tongue, thready pulse, and feverish sensations in the palms and soles, Shu Di (prepared Rehmannia) and Gou Qi Zi (Lycium Fruit) were added. The patients were administered one dose of the formula in decoction daily. After taking 3 to 39 doses, patients no longer experienced vertigo symptoms.(10)
Treating urinary system calculus
Li treated 30 cases of urinary system calculus with a modification of Wu Ling San. The modified formula consisted of Bai Zhu (Atractylodes), Fu Ling (Poria), Di Long (Earthworm), Gui Zhi (Cinnamon Twigs), Ze Xie (Alisma), Mang Xiao (Mirabilitum), Rou Gui (Cinnamon Bark), Zhu Ling (Polyporus), and Jin Qian Cao (Glechoma). For patients experiencing damp-heat symptoms, Huang Bo (Phellodendron) and Hu Zhang (Giant Knotweed Rhizome) were added. For those suffering insufficiency of yang, Ren Shen (Ginseng) and Shou Fu Zi (cooked Aconite) were added. For insufficiency of yin, Sheng Di (Rehmannia) and Shan Yu Rou (Cornus) were added. For qi stagnancy and blood stasis, Chuan Niu Xi (Achyranthes Chuan), Chuan Xiong (Cnidium), and E Zhu (Zedoaria) were added. And for hematuria, Di Yu Tan (Sanguisorba Carbon) and Hu Zhang (giant Knotweed Rhizome) were added. The patients were administered one dose of the formula daily. After treatment, 24 cases were resolved, 4 improved, and the remaining 2 cases did not respond to the treatment, with a total effectiveness rate of 93.3%.(11)