All Topics > Health > Traditional Chinese Medicine Herb > Zhu Ling >

Zhu Ling Louisiana

Zhu Ling can reduce the occurrence rate of B-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)-induced bladder tumors in rats, the number of tumors per rat, the tumor diameter, and the tumor malignity.

Local Companies

Mackie Shilstone Pro-Spa
504-679-7691
2111 Saint Charles Avenue
New Orleans, LA

Simply Nutrition
318-254-3468
730 Spring Creek Rd
Ruston, LA

Oc eaneering
(504) 201-4756
208 Amelia La, 70340
Amelia, LA

Personal Training By C J
337-912-1164
Lake, LA

Franco's Athletic Club
985-792-0200
100 Bon Temps Roule
Mandeville, LA

Pelican Athletic Club
985-626-3706
1170 Meadowbrook Boulevard
Mandeville, LA

WORKOUT EXPRESS
985-624-3433
1802 N. CAUSEWAY BLVD.
MANDEVILLE, LA

MAC Plaza
318-387-0590
1271 Lamy Lane
Monroe, LA

Monroe Athletic Club
318-387-2352
3801 Chauvin Lane
Monroe, LA

Moore Health and Fitness
318-324-9095
2318 Ferrand Street
Monroe, LA

Zhu Ling
Polyporus umbellatus (Grifola umbellatus), Polyporus Fungus

Dosage
Internal administration, 10 to 15g of the herb are taken in a decoction and administrated orally. 5:1 concentrated extract: 2-3 grams/day.

Toxicity
Carnogenic test: negative (PPS extract/mice/hypodermic or intraperitoneal injection, 0.5, 50mg/kg daily for 6 consecutive months). Teratogenic test: negative (PPS/mice/200mg/kg, intraperitoneal injection).(1)

Chemical Composition

Polyporusdextran I; Polyporusteron A, B, C, D, E, F, G; Ergosta-4, 6, 8(14), 22-tetraen-3-one; 25-deoxymakisterone A; 25-deoxy-24(28)-dehydromakisterone A; Ergosta-7, 22-dien-3-one; Ergosta-7, 22-dien-3-ol; Ergosta-5, 7, 22-trien-3-ol; 5a, 8a-epidioxyergosta-6, 22-dien-3-ol; a-hydroxytetracosanoic acid; 3, 4-dihydroxy benzaldehyde; Axungia; Isoleucine; Leucine; Aspartic acid; D-mannose; D-galactose; D-glucose.(2),(3),(4),(5) (6),(7)

Inorganic Chemicals
It contains trace elements, including calcium (Ca), phosphorus (P), copper (Cu), sodium (Na), potassium (K), and sulfur (S).

Precautions
Zhu Ling is contraindicated for interior dryness (lest causing injury to yin-fluids). Reported adverse effects of Zhu Ling include skin rashes, dermatitis, transient tinnitus, colporrhagia, systemic lupus erythematosus (SLE), arthritis, and arthralgia. (8),(9),(10),(11),(12),(13),(14),(15)

Pharmacology

Inhibitory effect on tumors

Zhu Ling can reduce the occurrence rate of B-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)-induced bladder tumors in rats, the number of tumors per rat, the tumor diameter, and the tumor malignity.(16) Experiments show that toxin-L extracted from the ascitic fluid of patients with primary hepatoma can cause notable fat hydrolysis in vitro, inhibit the ingestion functions of rats, decrease the serum zinc levels, and increase the serum copper levels. It has been established that toxin-L can produce neoplastic cachexia, and that polyporus polysaccharides can inhibit toxin-L's neoplastic cachexia-promoting activities.(17)

Enhancing immunity

Experiments on mice have shown that polyporus polysaccharides can enhance Concanavalin A and bacterial lipopolysaccharide-induced proliferation reactions of splenocytes, increase the number of specific antibody-secreting cells, enhance heterotypic splenocyte-induced hypersensitivity reactions, and enhance the killing capacity of splenotoxic T lymphocytes.(18) Experiments also have shown that polyporus polysaccharides can enhance the phagocytic and bactericidal functions of the human neutrophilic granulocytes,(19) and that it has a dose-dependent and interferon-g (TFN-g)-synergistic effects that promote the production of nitric oxide by the mice's macrophage.(20)

Anti-mutagenic and antidotal effects

When administered to mice by intraperitoneal injection at 0.8, 1.2, 1.6, and 4.0mg/kg, polyporus polysaccharides have inhibited cyclophosphamide-induced micronucleus formation with inhibition rates of 17.34%, 25.22%, 37.03%, 42.51%, and 55.12%, respectively.(21) Polyporus polysaccharides can also inhibit a cyclophosphamide-induced increase in the MNR of bone marrow PCE (perchloroethylene), and inhibit cyclophosphamide-induced decreases in white and red blood cell counts and hemalbumin (Hb).(22) When used in combination with cisplatin, polyporus polysaccharides can enhance the latter's inhibitory effect on transplanted S180, Lewis, and H22 tumors in mice, as well as reducing cisplatin's side effects (e.g., causing a drop in white blood count, atrophy of immune organs, and a reduction in the macrophage's phagocytic function).(23)

Liver-protecting effect

Experiments have shown that polyporus polysaccharides can lessen carbon tetrachloride (CCl4)- and D-aminogalactose-induced damage to liver tissues, and promote recovery from these damages. It has also promoted the generation of the hepatitis B surface antibody (HbsAb) in guinea pigs and Assamese macaques, and enhanced of the ability of celiac macrophage in normal and injured mice livers to release H2O2.(24),(25) When administered to mice by intraperitoneal injection at 0.25mg per mouse, polyporus polysaccharides have shown to have a moderate inhibitory effect on the expression of hepatitis B surface antigen (HbsAg) in the serum of hepatitis B virus (HBV)-transgenic mice.(26)

References

Li Min Min. A survey of research on Zhu Ling polysaccharides. Journal of Research Reference Material for Chinese Medicine. 1984;(4):1.
Da Ze Xiao Chen. Chemical composition of Zhu Ling. Foreign Medicine. 1991;13(3):47.
Editorial Committee of Chinese Materia Medica, State Drug Administration of China. Chinese Materia Medica. Shanghai Science and Technology Press, 1998.
Li Zhong You. Effects of herbal extract on hair growth and separation of Zhu Ling active components. Foreign Medicine. 1995;17(2):17-18.
Guo Shun Xing, et al. Determination of sugar levels in the sclerotium of wild and cultivated Zhu Ling of various ages. China Journal of Chinese Medicine. 1992;17(2):77-80, 126.
Guo Shun Xing, et al. An analysis of trace elements and amino acids in the sclerotium of wild and cultivated Zhu Ling of various ages. China Journal of Chinese Medicine. 1993;18(4):204-206.
Fang Li Xia. 2 cases of skin rashes caused by allergic reaction to Zhu Ling polysaccharides. Anhui Journal of Medicine. 1995;16(4):51.
Fan Guo Bin, et al. Allergic reactions to Zhu Ling polysaccharides. China Journal of New Herbal Medicine. 1995;4(6):44.
Yi Hong Yi, et al. One case of dermatitis caused by Zhu Ling polysaccharides. Journal of Infectious Diseases and Drugs. 1995;4(3):134.
Jiao Yun Xia, One case of allergic reaction and transient tinnitus caused by Zhu Ling polysaccharides. Journal of Infectious Diseases and Drugs. 1997;32(7):396.
Zhang Zhi Ping, et al. One case of colporrhagia caused by intramuscular injection of Zhu Ling polysaccharides. Journal of New Medicine and Clinical Application. 1995;14(3):183-184.
Dong Xian Ming, et al. One case of systemic lupus erythematosus caused by Zhu Ling polysaccharides. Northwestern Journal of Pharmacy. 1998;13(2):63.
Fan Guo Bin. One case of severe arthralgia caused by Zhu Ling polysaccharide. Journal of Modern Applied Pharmacy. 1996;13(2):63.
Leng Zuan You, et al. One case of arthritis caused by Zhu Ling polysaccharides. China Journal of New Herbal Medicine. 1998;7(1):78.
Yang De An, et al. Zhu Ling's effects on bladder tumor. China Journal of External Medicine. 1991;29(6):393-395.
Wu Geng Shu, et al. Zhu Ling polysaccharide's inhibition on toxin L-induced neoplastic cachexia. China Journal of Integrated Medicine. 1997;17(4):232-233.
Gao Mei, et al. Zhu Ling polysaccharide's effect on mice's immune functions. China Journal of Immunology. 1991;7(3):185-187.
Zhang Li Ping, et al. The effect of selected Chinese herbal extracts on the antibacterial function of human PMN phagocytes. China Journal of Microbiology and Immunology. 1994;(4):227-279.
Hou Gan, et al. Zhu Ling polysaccharide's effect on carbon monoxide formation in mice's abdominal macrophagocytes. China Journal of Geriatrics. 2000;20(4):233-235.
Zhang Hui, et al. The anti-mutagenic effect of Zhu Ling polysaccharide. Journal of Chinese Patented Medicine. 1993;15(3):29.
Bo Xin, et al. The effects of Sha Shen, Sha Ren, Zhu Ling, E Zhu, and Ji Xue Teng on cyclophosphamide's side effects. China Journal of TCM Science and Technology. 1997;4(3):153-154, 175.
Wang Yan, et al. Zhu Ling polysaccharide's synergistic effect with cisplatin. Journal of Traditional Chinese Medicine Research. 1996;(5):60-61.
Yan Shu Chang, et al. Zhu Ling polysaccharide's effect on chronic viral hepatitis. Journal of Integrated Medicine. 1988;8(3):141-143.
Zhang Ying Hua, et al. Effects of Zhu Ling polysaccharides on mononuclear macrophagocytes in mice with liver injuries. Journal of Integrated Medicine. 1991;11(4):225-226, 198.
Guo Chang Zhan, et al. Zhu Ling polysaccharides' effects on HBs Ag expression in HBV transgenic mice. China Journal of Experimental Clinical Immunology. 1999;10(6):368-370.

This information is educational in context and is not to be used to diagnose, treat or cure any disease. Please consult your licensed health care practitioner before using this or any medical information.

Featured Local Company

Mackie Shilstone Pro-Spa

504-679-7691
2111 Saint Charles Avenue
New Orleans, LA
A full-service facility with a non-intimidating environment. Daily locker & towel service is always complimentary. Each locker room has its own whirlpool dry sauna and steam room.

Read more about Zhu Ling

- Shen Ling Bai Zhu San Louisiana

This formula's main function is to enforce the spleen and stomach and to invigorate lung qi.

- Wu Ling San Louisiana
- Carpal Tunnel Syndrome Louisiana
- Wei Ling Xian Louisiana
- Gui Zhi Fu Ling Wan Louisiana
- Osteoporosis Louisiana
- Edema Louisiana
- Congestive Heart Failure (CHF) Louisiana
- Jia Kang Ling Pian Louisiana
- Fu Ling Louisiana

Regional Articles

- Zhu Ling Abbeville LA
- Zhu Ling Alexandria LA
- Zhu Ling Baker LA
- Zhu Ling Bastrop LA
- Zhu Ling Baton Rouge LA
- Zhu Ling Bogalusa LA
- Zhu Ling Bossier City LA
- Zhu Ling Breaux Bridge LA
- Zhu Ling Carencro LA
- Zhu Ling Chalmette LA
- Zhu Ling Covington LA
- Zhu Ling Crowley LA
- Zhu Ling Denham Springs LA
- Zhu Ling Deridder LA
- Zhu Ling Eunice LA
- Zhu Ling Franklinton LA
- Zhu Ling Gonzales LA
- Zhu Ling Gretna LA
- Zhu Ling Hammond LA
- Zhu Ling Harvey LA
- Zhu Ling Haughton LA
- Zhu Ling Houma LA
- Zhu Ling Jennings LA
- Zhu Ling Kenner LA
- Zhu Ling La Place LA
- Zhu Ling Lafayette LA
- Zhu Ling Lake Charles LA
- Zhu Ling Leesville LA
- Zhu Ling Mandeville LA
- Zhu Ling Marrero LA
- Zhu Ling Metairie LA
- Zhu Ling Minden LA
- Zhu Ling Monroe LA
- Zhu Ling Morgan City LA
- Zhu Ling Natchitoches LA
- Zhu Ling New Iberia LA
- Zhu Ling New Orleans LA
- Zhu Ling Opelousas LA
- Zhu Ling Pineville LA
- Zhu Ling Plaquemine LA
- Zhu Ling Ponchatoula LA
- Zhu Ling Prairieville LA
- Zhu Ling Rayne LA
- Zhu Ling Ruston LA
- Zhu Ling Saint Martinville LA
- Zhu Ling Shreveport LA
- Zhu Ling Slidell LA
- Zhu Ling Sulphur LA
- Zhu Ling Thibodaux LA
- Zhu Ling Ville Platte LA
- Zhu Ling Walker LA
- Zhu Ling West Monroe LA
- Zhu Ling Westwego LA
- Zhu Ling Zachary LA

- Congestive Heart Failure (CHF) Louisiana

Congestive heart failure is a condition that occurs at the late stages of heart disease, when myocardial contraction is significantly weakened, and the cardiac output so severely diminished as not to meet the blood demand by the body's tissue cell metabolism.

- Osteoporosis Louisiana
- Shen Ling Bai Zhu San Louisiana
- Gui Zhi Fu Ling Wan Louisiana
- Wu Ling San Louisiana
- Edema Louisiana
- Fu Ling Louisiana
- Carpal Tunnel Syndrome Louisiana
- Wei Ling Xian Louisiana
- Jia Kang Ling Pian Louisiana

Related Local Events

Congress of Neurological Surgeons 2009 Annual Meeting
Dates: 10/24/2009 - 10/29/2009
Location: Ernest N. Morial Convention Center
New Orleans, LA
View Details

CHIs The Bioprocessing Summit
Dates: 8/24/2009 - 8/27/2009
Location: Royal Sonesta Hotel
New Orleans, LA
View Details

Acadiana Great Outdoors Expo
Dates: 8/21/2009 - 8/23/2009
Location: Cajundome & Convention Center
Lafayette, LA
View Details

Shreveport Hunters Expo
Dates: 7/24/2009 - 7/26/2009
Location: Shreveport Convention Center
Shreveport, LA
View Details

Club and Hotel Controllers Conference
Dates: 6/23/2009 - 6/24/2009
Location: New Orleans Convention Center
New Orleans, LA
View Details

Advertising	Food & Beverage	Nightlife
Business Services	Franchise	Online Database
Career	Health	Pets
Cars	Holidays	Real Estate Resources
Computer Hardware	Home Appliances	Retail & Consumer Services
Construction	Home Electronics	Software
Education	Home Services	Technology
Entertainment	Industrial Goods & Services	Telecommunications
Environmental	Insurance	Trade Shows
Family	Internet	Travel
Fashion	Legal	Weddings
Financial Services	Miscellaneous	World History

Advertising	Family	Home Services	Real Estate Resources
Business Services	Fashion	Industrial Goods & Services	Retail & Consumer Services
Career	Financial Services	Insurance	Software
Cars	Food & Beverage	Internet	Technology
Computer Hardware	Franchise	Legal	Telecommunications
Construction	Health	Miscellaneous	Trade Shows
Education	Holidays	Nightlife	Travel
Entertainment	Home Appliances	Online Database	Weddings
Environmental	Home Electronics	Pets	World History